What’s good for the body is good for the brain, and nowhere is that more apparent than in what you put in your mouth. Food, after all, has a powerful effect on your brain, so much that it can often help lift that mood. The one caveat? The positive effects come from eating plant-based foods.

Depression, of course, isn’t to be taken lightly and should be treated by seeking professional help. Even just mild depression can create physical or emotional issues, and while there are certain medications known to be effective, doctors now are also prescribing dietary changes for mood disorders, from anxiety to mild depression and everything in between. Studies have found that certain plants can be an effective part of your feel-good strategies. “A plant-rich diet can change brain chemistry in a way that gets your mood on a more even keel,” says Neal Barnard, M.D., president of the Physicians Committee for Responsible Medicine (PCRM), founder of the Barnard Medical Center in Washington, D.C., and author of "Your Body in Balance" (Grand Central, 2020).

Diet and Brain Chemistry

But how exactly do plants change brain chemistry? The answer has to do with inflammation. “People who are depressed have indicators of inflammation in the brain, which can cause chemical changes in the brain,” Barnard says. Yet plants are loaded with strong anti-inflammatory compounds that can often eliminate or reduce that inflammation. By eating more plants and less or no meat, you’re also improving your gut microbiome, which sends signals directly to the brain, possibly improving mood as a result. 

While the mood-elevating effects of plants haven’t yet been compared to medications, numerous studies support the mood lift from plant-based diets. Barnard points to research PCRM did with GEICO employees who not only lost weight and improved diabetes measures after adopting a plant-based diet but also felt depression, even anxiety, lift. Why? Of course, they were improving health and losing weight, which would make anybody feel better, but there was more to the picture, and it wasn’t just the addition of plants but also the absence of meat. “The more you load your plate with plants, the less room you’ll have for animal products, which is beneficial for the brain,” he says.

Want to optimize the mood-boosting benefits of plants? Follow these five tips:

Fried tofu in bowl, Vegetarian food
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1. Enjoy Soy

Studies of women in Asia found that eating a diet rich in soy appears to lower the risk of depression, and that the isoflavones in soy seem to act as mood stabilizers. 

Only limited research has evaluated the impact of soy or isoflavone intake on depression although several studies from China and Japan did find that the amount of soy in your diet is inversely related to your risk of depression.

The incidence of depression was a secondary outcome in the studies, which further supports the idea that in studies where the risk of depression was the primary topic studied, isoflavones significantly improved symptoms. 

Bottom Line: Isoflavones, found in products like tofu, tempeh, and soymilk, have been shown to stabilize mood. Two to four servings a day seem to do the trick, according to Dr. Barnard

Mango quinoa salad with rocket, avocado, cucumber, red radishes and pumpkin seeds
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2. Fiber it up

When you eat more plants, you’ll automatically eat more fiber. After all, fiber is only found in plants, but here’s why that’s key: In one study from the journal Nutrition, as people increased their fiber intake, their risk of depression decreased. “When you increase your fiber intake to 25 to 30 grams a day, risk of depression is reduced by 60 to 70 percent,” Barnard says.

Make easy swaps | Getty Images/iStockphoto
Make easy swaps | Getty Images/iStockphoto

3. Choose plant over animal protein

One study found that folks eating less meat suffered less depression with plant-strong diets reducing risk of depression by 26 percent, Barnard says. Some studies suggest that noshing a serving of plant protein in the morning may help keep your mood stable throughout the day which is why you might consider adding soymilk, veggie sausage, beans, chickpeas, hummus, or scrambled tofu to your morning meal. 

Find folate in foods like broccoli | Getty Images

4. Focus on folate

It’s key to eat a variety of plant foods, but there’s good reason to add foods that are rich in folate like asparagus, spinach, broccoli, beans, chickpeas, lentils, and peas. Studies show that folate deficiency may actually contribute to depression.

Close-Up Of Vegetables For Sale
Eat the rainbow Getty Images/EyeEm

5. Power up with produce

Folks who eat more fruits and veggies, staples in a plant-only diet, experience improved mental well-being, according to a study in Social Science & Medicine.

The message is clear: Load your plate with plants, and among other things, your mood could soon be on the upswing, even as early as a few days. Regardless of whether that’s from actual changes in the brain or other changes that happen when you shift to plant-only eating, you’ll undoubtedly feel better, and that alone is worth the transition.